These sell for $349/$379 at local stores. As mentioned in a previous Etymotic deal, be aware that the eartips can take some getting used to as they go deep into the ear canal.
The ER3SE is the more neutral version of Etymotic's ER3 range. The video review below suggests these are best for Classical/Opera/Acoustic type music. If you listen to modern pop or dance, their suitability may depend on your sensitivity to higher frequencies. Look at the ER3XR instead if this is the case or if you really love your bass.
A good short video review comparing the ER3SE and ER3XR.
"The Etymotic ER3SE addresses the needs of music lovers seeking quality, with an impressively clean sound character. The manufacturer claims to create tools for professionals and this is reflected in the tuning of these in-ears. These headphones deliver an honest and unembellished sound that will impress. What’s more, wearing comfort scores highly. If you can do without the frills and features you might otherwise expect as standard, these are well worth considering."
"With the ER3, Etymotic has delivered a very accessible and great sounding, typically Etymotic house sound tuned IEM. Another well done IEM, congrats!"